fatal idiopathic hypereosinophilic syndrome presenting with refractory ascites : case report study
نویسندگان
چکیده
hypereosinophilic syndromes were a group of divergent disorders united by overproduction of eosinophils and the several organ damages ascribed to this persistent eosinophilia. among all the presenting symptoms, gastrointestinal symptoms were the least common. we were reporting a 21 year old man with a 2 year history of refractory ascites, hepatomegaly, portal and hepatic veins thrombosis and cutaneous lesions. bone marrow aspiration and biopsy revealed granulocytic hyperplasia with marked eosinophilia. after ruling out common causes of eosinophilia, a diagnosis of idiopathic hypereosinophilic syndrome was made. the patient was treated with corticosteroids and imatinib but due to the advanced progression of the disease, resulted in a fatal outcome. since early diagnosis and treatment is the key for improving the prognosis of hes patients, a high clinical suspicion is necessary in the diagnosis of this condition. keywords: eosinophilia, hypereosinophilic syndrome (hes), refractory ascites
منابع مشابه
Idiopathic Hypereosinophilic Syndrome
Idiopathic hypereosinophilic syndrome is a multisystem disease with peripheral blood eosinophilia of at least 6 months duration, multiple organ system involvement, and no evidence for other known causes of eosinophilia. It is characteristically a disease of middle-aged men, often has a poor prognosis and is seldom found during childhood. Heart dicsease, characterized by endomyocardial fibrosis ...
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عنوان ژورنال:
گوارشجلد ۲۰، شماره ۴، صفحات ۲۷۴-۰
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